Miscellaneous agents differ from any of the major classes of cytotoxic agents.
Common miscellaneous agents are asparaginase and hydroxyurea.1, 7, 11
Topoisomerase inhibitors prevent realigning of DNA strands and maintain single-strand breaks. Major toxicities occur in the haematopoietic and gastrointestinal systems. Examples include irinotecan and topotecan.1, 7, 11
Choose a miscellaneous agent and discuss the:
- Indications in cancer control.
- Mechanism of action.
- Adverse effects.
- Administration considerations.